Bone loss occurs over time and is a result of an imbalance in the activity of bone cells where there is an increased activity in the bone dissolving cells called osteoclasts as well as a corresponding decrease in the activity of bone forming cells, or osteoblasts. Vitamin K is necessary for healthy bone mineral density. Vitamin K has been shown to be essential for bone mineralization because it isIngredients:Supplement Facts Serving Size:4 CapsulesAmount Per Serving%Daily ValueVitamin D3 [as cholecalciferol (1000 IU)]25 mcg 125%Vitamin K2 [as menaquinone-4 (45 mg)]45,000 mcg 37,500%Calcium [as calcium carbonate, calcium citrate malate, calcium bisglycinate chelate, calcium fructoborate]700 mg 54%Magnesium [as magnesium oxide]300 mg 71%Zinc [as zinc amino acid chelate]2 mg 18%Manganese [as manganese amino acid chelate]1 mg 43%Silicon [from horsetail extract (herb)]5 mg **Boron [as patented Fruitex B? OsteoBoron calcium fructoborate]3 mg ****Daily Value not established. Other Ingredients: Vegetable cellulose (capsule), malic acid, microcrystalline cellulose, citric acid, maltodextrin, vegetable stearate, glycine, rice flour, modified starch.