Optivite PMT is the first multivitamin - multimineral supplement formulated for use by women with Premenstrual tension syndromes (PMTS). Available to PMTS sufferers over the past 20 years, Optivite underwent several clinical studies published in peer-reviewed medical journals: 3 open trials and 2 double blind placebo-controlled studies.A 50% reduction of PMTS complaints has been observed in those studies following 1 to 3 months on this supplement.When 313 PMTS sufferers were followed for up to 5 years on this program, an interesting observation was that the number of tablets of Optivite required to maintain the improvement in PMTS complaints decreased over time: 5. 2 + 0. 36 tablets between 2 and 6 months: 4. 8 + 0. 6 tablets between 7 and 12 months: 4. 3 + 0. 48 tablets between 13 and 24 months and 3. 2 + 0. 34 tablets over 24 months.With over 100,000 women on this program during the first 5 years of availability of Optivite , not a single documented case of Vitamin A toxicity and peripheral neuropathy due to Vitamin B-6 has been reported.Optivite is recommended as part of a total dietary program to obtain best results. Suggested Use: Read all package and warnings before use and use only as directed:Adults: Six tablets daily with meals as a dietary supplement, or as directed by a physician. UPC: 350520001033 Weight: 0.78 lbs