SAM-e is a vital substance that's found in most of your cells and is essential to many biochemical reactions in the body. Because of that, it serves many roles including promoting joint comfort and liver health but it's worth noting that SAM-e can support emotional well-being as well.* Discovered by Italian scientist Giulio Cantoni in 1952, SAM-e has been used extensively in Europe for more than 20 years. SAM-e may play a role in increasing the synthesis and breakdown of certain neurotransmitters and enhance the sensitivity of nerve receptors in the brain.* To put it simply, SAM-e could help in supporting your mood.* Because of age or other factors, levels of SAM-e can fluctuate or decline. And since SAM-e is not readily available in an everyday diet, a supplement may be just what you need to keep you moving with ease and feeling sunny and healthy.