Prime is the complete and concentrated conditioner for both fresh and salt water. Prime removes chlorine, chloramine and ammonia. Prime converts ammonia into a safe, non-toxic form that is readily removed by the tank's biofilter. Prime may be used during tank cycling to alleviate ammonia/nitrite toxicity. Prime detoxifies nitrite and nitrate, allowing the biofilter to more efficiently remove them. Prime also promotes the production and regeneration of the natural slime coat. Prime is non-acidic and will not impact pH. Prime will not overactivate skimmers. Use at start-up and whenever adding or replacing water. As part of their ongoing environmental stewardship efforts Seachem will donate a portion of the profits for every specially labeled edition bottle of Prime, Stability, Pristine, and Clarity (in Bonus Sizes of 325 mL -- 30% more) sold to a Rhino preserve in South Africa. SPECIAL BONUS SIZE - GET 30% MORE FREE . As part of our ongoing environmental stewardship efforts, Seachem has joined the battle to support the protection of these endangered animals. We are pleased to announce specially labeled editions of Prime, Stability, Pristine, and Clarity - in Bonus Sizes of 325 mL (30% more). Seachem will donate a portion of the profits for every bottle sold to a Rhino preserve in South Africa. By donating directly, we can maximize the donated funds made available for the preserve.